Researchers discover protein that could help prevent the spread of cancer
A protein capable of halting the spread of breast cancer cells could lead to a therapy for preventing or limiting the spread of the disease.
View ArticleA gene implicated in speech regulates connectivity of the developing brain
Foxp2, a gene involved in speech and language, helps regulate the wiring of neurons in the brain, according to a study which will be published on July 7th in the open-access journal PLoS Genetics. The...
View ArticleCancer stem cells recruit normal stem cells to fuel ovarian cancer
Researchers at the University of Michigan Comprehensive Cancer Center have found that a type of normal stem cell fuels ovarian cancer by encouraging cancer stem cells to grow.
View ArticleThe tangled web in Alzheimer's protein deposits is more complex than once...
Scientists from the National Institutes of Health in the United States have made an important discovery that should forever change the scope and direction of Alzheimer's research. Specifically, they...
View ArticleNew study uncovers how brain cells degrade dangerous protein aggregates
Researchers at the RIKEN Brain Science Institute (BSI) have discovered a key mechanism responsible for selectively degrading aggregates of ubiquitinated proteins from the cell. Their findings indicate...
View ArticleResearchers identify novel pathway responsible for infection of a common STD...
Researchers from Boston University School of Medicine (BUSM) have for the first time identified a novel pathway that is necessary for infection to occur with the pathogen Neisseria gonorrhoeae, which...
View ArticleStudy identifies genetic variants linked to fatty liver disease in obese...
New research found the genetic variant Patatin-like phospholipase domain containing protein-3 (PNPLA3) acting in conjunction with the glucokinase regulatory protein (GCKR) is associated with increased...
View ArticleProbing the roots of depression by tracking serotonin regulation at a new level
In a process akin to belling an infinitesimal cat, scientists have managed to tag a protein that regulates the neurotransmitter serotonin with tiny fluorescent beads, allowing them to track the...
View ArticleFragile X study offers new drug hope
(Medical Xpress)—An experimental drug can improve sociability in patients with fragile X syndrome and may be helpful as a treatment for autism, according to a study.
View ArticleSearch for epigenetic decoder leads scientists to Rett Syndrome
(Medical Xpress)—A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at...
View ArticleLack of iron regulating protein contributes to high blood pressure of the lungs
A protein known to regulate iron levels in the body has an unexpectedly important role in preventing a form of high blood pressure that affects the lungs, and in stabilizing the concentration of red...
View Article'RNA sponge' mechanism may cause ALS/FTD neurodegeneration
The most common genetic cause of both ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) was recently identified as an alteration in the gene C9orf72. But how the mutation causes...
View ArticleOncogene mutation hijacks splicing process to promote growth and survival
An international team of researchers – led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the...
View ArticleResearchers pinpoint how smoking causes osteoporosis
(Medical Xpress)—Human bone breaks down and regenerates naturally all the time, in a perfectly balanced dance that maintains skeletal integrity.
View ArticleMeet CLAMP: A newly found protein that regulates genes
(Medical Xpress)—A newly discovered protein, found in many species, turns out to be the missing link that allows a key regulatory complex to find and operate on the lone X chromosome of male fruit...
View ArticleStudy examines ways to restore immunity to chronic hepatitis C infection
The hepatitis C virus hijacks the body's immune system, leaving T cells unable to function. A new study in animal models suggests that blocking a protein that helps the virus thrive could restore...
View ArticleA small molecule may help reduce damage in aging-related heart attacks
(Medical Xpress)—A small molecule developed at Yale University to limit damage done by ischemia – restricted blood flow – during heart attacks or surgery has been shown to reduce by 40 percent the...
View ArticleRare childhood disease may hold clues to treating Alzheimer's and Parkinson's
Scientists at Rutgers University studying the cause of a rare childhood disease that leaves children unable to walk by adolescence say new findings may provide clues to understanding more common...
View ArticleProtein seipin regulates fat development through cytoskeleton remodeling
People with mutations in a gene called BSCL2 suffer from a rare medical condition known as lipodystrophy in which fat tissue is lost from where it is supposed to accumulate while being deposited at...
View ArticleDetailed studies reveal how key cancer-fighting protein is held in check
St. Jude Children's Research Hospital scientists have mapped the structural details of how p53 attaches to its regulatory protein, called BCL-xL, in the cell. The protein p53 is a key activator of the...
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